Searching for Depression's Holy Grail. After seventeen years of therapy and medication, I'm done. Therapy was fine but after so long it becomes redundant. Medication, I've decided, is like putting on a band-aid when you look down and realize that your intestines are spilling out. Here are my experiences with meditation, mindfulness, 5-MTHF (a Folic Acid supplement), and the basic re-training of my mind to beat depression.